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Antiinflamm Antiallergy Agents Med Chem ; 20(2): 118-122, 2021.
Article in English | MEDLINE | ID: covidwho-955331

ABSTRACT

Novel Corona Virus 2019 (COVID-19) is a new virus spread rapidly all over the world. It has specific respiratory or gastrointestinal tract symptoms. Its reported complications include respiratory distress, systemic inflammatory response syndrome, and septic shock. Due to heavy cytokines released by the virus; corticosteroids (40-120 mg / day) were given to severe cases to reduce pneumonia. It's a difficult task to control the spread of SARS-CoV-2, and to invent proper vaccines and treatments. In this review, the existing understanding of fatal, pandemic human coronavirus SARS-Cov2 (COVID-19), with special reference to its diagnosis, origin, transmission, and different approaches to develop its therapeutics, will be discussed.


Subject(s)
COVID-19/epidemiology , COVID-19/physiopathology , Adrenal Cortex Hormones/therapeutic use , COVID-19/mortality , Cytokines/biosynthesis , Humans , Pandemics , Respiratory Distress Syndrome/physiopathology , SARS-CoV-2 , Shock, Septic/physiopathology , Systemic Inflammatory Response Syndrome/physiopathology , COVID-19 Drug Treatment
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